Contraindications: hypersensitivity to any component of the vaccine (as well as to yeast), if complications were detected after previous vaccination. Vaccination is not given to children who have diseases accompanied by fever. HIV infection is not a contraindication to hepatitis B vaccination.

Side effects: after vaccination, there may be a slight increase in temperature, irritability, redness, rash, swelling, pain and / or swelling at the injection site, loss of appetite, drowsiness, nausea, headache. In the presence of mechanical inclusions or a strange color of the solution, the use of the vaccine is unacceptable.