Contraindications: TWINRIX ™ should not be administered to persons with hypersensitivity to the components or neomycin, as well as to persons who have shown signs of hypersensitivity after the first administration of TWINRIX ™ vaccine or monovalent vaccines for the prevention of hepatitis A and B. As with other vaccines, administration of TWINRIX ™ vaccine should be delayed in individuals with acute febrile illness.

Side effects: after vaccination, a feeling of fatigue, headache, weakness, fever, nausea, redness, tightness at the injection site, pain at the injection site may be observed. In the presence of mechanical inclusions or a strange color of the suspension, the use of the vaccine is unacceptable.